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Depending on the drug, the effectiveness of one or both medications may be compromised or increased to an undesirable level.
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WAS ON TOPMAX LAS T YEAR, 25 MGS FIRST FOR A MONTH, THEN 50 MGS FOR 3 MONTHS, I LOST 30 POUNDS WHICH I HAVE BEEN TRYING FOR 2 YRS!
Most clinicians shoot for a dose range of 100-200 mg QD to maximize response while minimizing side effects.
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For most of us the side effects do ease - but it does take time - I only increased the dose when I felt each awful side effect beginning to ease, then I went up as couldn't cope otherwise - but it was a bumpy ride but really worth it as my migraines are doing a lot better now!
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